K-9 MWD™ SAMe Liver 425mg

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Natural SAMe

S-Adenosylmethionine

Pharmaceutical Grade Active S,S Isomer

Natural and Gentle Plant derived enteric coating

100% Vegetarian

200MG or 400MG – 60 Tablets

Healthy Liver & Detoxification

Can Help in as little as 1-2 weeks when taken daily.

Product Certificates

 

MADE FROM NATURE, PROVEN BY SCIENCE, RECOMMENDED BY PROFESSIONALS.

Daily Recommended Dosage: Take 1-2 tablets per day, or as recommended by your certified health care provider.   If your SAMe levels are deficient and to determine the proper dose that works for you, use an initial loading phase of 1200mg-1600mg (3-5 tablets) daily (maximum 1600mg/day) for up to two weeks then reduce daily intake to 400mg-800mg (1-2 tablets), until benefits are achieved.

Samesyl™ supports the replenishment of S-Adenosylmethionine levels and balances the interactions of your immune system, maintains cell membranes, and helps produce and break down brain chemicals, such as serotonin, melatonin, and dopamine.  S-Adenosylmethionine (SAMe) is a naturally occurring compound that is found in almost every tissue and fluid in the body.*

Samesyl™ SAMe significantly increases the liver’s glutathione level.  This is critical because glutathione is the chief antioxidant produced in the liver, also known as the “super antioxidant”.   Age, stress, free radicals and environmental conditions can dramatically impact the liver’s health and accelerate the aging process. Samesyl™ SAMe is converted into glutathione, thus having the therapeutic benefits for the liver to combat oxidative stress, cellular damage, free radical activity and DNA breakdown, allowing the body to detoxify.  This is one reason why SAMe supplement may be helpful in replenishing the necessary supply your body needs to help maintain or restore healthy liver functions and detoxification.*

Samesyl™ is formulated with Pharmaceutical Grade S-Adenosylmethionine.  SAM-e is made naturally by microbiological fermentation and then specially processed in a ultra-low moisture and temperature controlled clean-room to preserve 68-80% (S,S) SAMe, the highest active level available. Samesyl™ natural plant based enteric coating is formulated to pH release in the small intestine for maximum bioavailability and absorption.*

Samesyl™ is the only SAMe with a Natural Plant based coating.  No plastic co-polymer coating material- only pure Pharmaceutical Grade SAMe and Natural Gentle Plant derived enteric coating materials.*

Serving Size: 1 Tablet

Servings Per container: 60

	Amount per Tablet	% Daily Value*
SAMe (S-Adenosylmethionine) (from 850mg of S-Adenosylmethionine Disulfate Tosylate)	425MG	†
SAMe (S-Adenosylmethionine) (from 450mg of S-Adenosylmethionine Disulfate Tosylate)	225MG	†

* Percent Daily Values are based on 2,000-calorie diet.

† Daily Value not established.

Other Ingredients:  Microcrystalline Cellulose, Crospovidone, Colloidal Silicon Dioxide, Magnesium Stearate

Enteric Coating:  Ethylcellulose (Plant Source), Medium Chain Triglycerides (Vegetable Source), Oleic Acid (Vegetable Source), Hypromellose, Talc, Hydroxypropl Cellulose, Sodium Alginate (Plant Source), Purified Stearic Acid.

Allergenic Ingredients:  No sugar, no starch, no artificial flavors, no preservatives, sodium free, no wheat, no gluten, no corn, no soy, no dairy, yeast free, no lactose, no artificial colorant.

 

Administration of K-9 V Tablets

Because the tablet must be kept intact to prevent destruction by moisture, administration range is based on the nearest whole-tablet. The chart below is provided as a guide for administration. Daily administration may also be calculated based on 20 mg/kg of body weight and rounded to the closest tablet size or combination of sizes.

K-9 V Canine and Feline Daily* Administration Guide

For cats and small dogs 225 mg – broken in half

Body Weight	Body Weight	Number of Tables per day
Up to 12 lb	Up to 5.5 kg	1 Tablet

For medium dogs 225 mg

Body Weight	Body Weight	Number of Tables per day
13-34 lb	6-15.5 kg	1 Tablet

For large dogs 425 mg

Body Weight	Body Weight	Number of Tables per day
35-65 lb	16-29.5 kg	1 Tablet
66-120 lb	30-54.5 kg	2 Tablets
Over 120 lb	Over 54.5 kg	3 Tablets

* The number of tablets can be gradually reduced or increased at any time depending on pet’s needs.

Many pets are maintained long-term on ever-other-day or every-third-day administration.

 

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For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. Studies have shown that, in many cases, tablets or capsules given as a “dry swallow” do not pass into the stomach in cats but may become lodged in the esophagus. It is recommended for pet owners to administer 3-6 cc of water immediately following any tablet administration to speed passage of the tablet into the stomach.6,7 K-9 V 225 mg tablets broken in half are ideal for cats because of their small size. If the pet is to receive more than one tablet daily, the total number of tablets may be divided between morning and evening for ease of administration. For example, a daily administration of three tablets could be divided into two tablets in the morning and one tablet in the evening.

 

Storage

Keep out of reach of children.  Store in a cool, dry place.

Packaging

Aluminum-Aluminum tamper resistance blister card.  Samesyl SAMe tablets should be kept in the blister card until you take them.  Do not take tablet, if the blister card compartment for that tablet has been tampered or compromised.

WARNING: Please consult your certified and knowledgeable healthcare practitioner before taking any dietary supplement.  Keep out of reach of children.  Do not use if blister card is compromised.

• Supports normal healthy liver function and homocysteine levels
• SAMe’s extraordinary capacity to support and enhance liver function
• SAMe is thought to be beneficial for those with liver disease by acting as a precursor of antioxidant glutathione; repairing the mitochondrial glutathione transport system; inhibiting the toxic effects of proinflammatory cytokines; and increasing DNA methylation.
• There are nearly a thousand published studies documenting SAMe’s ability to support therapeutic improvement in liver disease.
• SAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function, including phase II detoxification.*